Cell Culture Growth Factors and Hormones
Cayman Chemical ThrombIn RECPTR PeptID LIg 1mg
An antagonist of the thrombin receptor (EC50s = 16-33 µM); inhibits α-thrombin and TRAP-induced platelet aggregation in vitro at 32 µM; inhibits arterial thrombosis in a rabbit model of partial carotid artery occlusion at 100 µmol/kg bolus, i.v., plus 900 µmol/kg infusion)
Medchemexpress LLC IFN-lambda 1/IL-29 50ug
IFN-lambda 1 (IL-29) is a member of the Type-III interferon family IFN-lambda 1 signals through a heterodimeric receptor complex comprising IFN receptor 1 (IFNLR1) and IL-10 receptor subunit- (IL-10RB) When IFN-lambda 1 binds with the receptor complex Jak1 and Tyk2 will be activated and leads to subsequent tyrosine phosphorylation of the IFN- R1 and activation of STAT1 and STAT2[1] IFN-lambda 1 modulates immunity in infections and autoimmune diseases[2] IFN-lambda 1/IL-29 Protein Human (HEK293 His) is a recombinant human IFN-lambda 1 (G20-T200) with C-terminal 10 His tag which is produced in HEK293
Biocare Medical, LLC IGF-1R Antibody - Concentrate, 1.0 ml
The Insulin-like Growth Factor 1 Receptor (IGF-1R antibody) is a trans-membrane receptor that is activated by Insulin-like Growth Factor (IGF-1 antibody). IGF-1 stimulates mitosis and inhibits apoptosis thus enhancing cell survival. It is expressed in all tissues and is highly over-expressed in most malignant tissues. IGF-1 has been shown to induce hypoxia-inducible factor-1 (HIF-1) mediated vascular endothelial growth factor (VEGF) expression. Studies show IGF-1 to be a likely predictor for resistance to anti-EGFR antibody treatment in K-RAS wild type colorectal cancer. IGF-1 and K-RAS analysis may offer an effective strategy for selection of responding colorectal cancer patients.
OriGene Fibroblast activation protein, alpha (FAP) (NM_004460) Human Untagged Clone, 10ug
FAP (untagged)-Human fibroblast activation protein, alpha (FAP)
Medchemexpress LLC EGF Human HEK293 5ug
The Progranulin/PGRN protein is involved in a variety of cellular processes including cell growth inflammation and neurodegeneration It acts as a regulator of tissue repair and has been implicated in the pathogenesis of several diseases including Alzheimer s disease and frontotemporal dementia Progranulin/PGRN interacts with various receptors and signaling pathways to exert its effects on cellular function and disease progression EGF Protein Human (HEK293 N-hFc) is the recombinant human-derived EGF protein expressed by HEK293 with N-hFc labeled tag